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喜讯!夺宝岛BPI-17509项目I期临床试验第一例受试者入组
日期: 2020-07-13

     7YUE13RI,夺宝岛GUFENYOUXIANGONGSIXINYAOBPI-17509XIANGMUIQILINCHUANGSHIYANDIYILISHOUSHIZHECHENGGONGRUZU。GAIYANJIUMINGWEI“BPI-17509ZAIWANQISHITILIUHUANZHEZHONGDE I QILINCHUANGYANJIU”,ZHUYAOYANJIUZHEWEIBEIJINGZHONGLIUYIYUANDESHENLINJIAOSHOU。SHIYANBAOKUOJILIANGDIZENGYANJIUHEKUODARUZUYANJIU,ZHUYAOYANJIUMUBIAOSHIPINGGUBPI-17509DEANQUANXINGHENAISHOUXING,QUEDINGZUIDANAISHOUJILIANG(MTD)HEJILIANGXIANZHIXINGDUXING(DLTs),YIJIPINGGUCHUBULIAOXIAO,QUEDINGIIQILINCHUANGSHIYANTUIJIANJILIANG(RP2D)。 

 BPI-17509作用机理图

       BPI-17509SHI夺宝岛ZIZHUYANFADEYONGYOUQUANXINHUAXUEJIEGOUDECHENGXIANWEIXIBAOSHENGZHANGYINZISHOUTI(FGFR1/2/3)XIAOFENZIKOUFUYIZHIJI,NIYONGYUXIEDAIFGFRJIYINBIANYIDEGANNEIDANGUANAI、BANGGUANGAIHEFEILINAIDENGSHITILIUZHILIAO。FGFRSHUYULAOANSUANSHOUTIJIMEIJIAZU,BAOKUOSIZHONGSHOUTIYAXING(FGFR-1、2、3JI4)YIJIYIXIEYIGOUFENZI,ZAIZHONGLIUZENGZHI、XUEGUANSHENGCHENG、QIANYIHECUNHUOZHONGQIZHEZHIGUANZHONGYAODEZUOYONG。BPI-17509TONGGUOTEYIXINGYIZHIFGFR1/2/3DEHUOXING,ZUZHIXIANGGUANXINHAOCHUANDAODETUJING,JINERYINGXIANGSHENGWUTINEIXIBAOZENGZHI、DIAOWANG、QIANYI、XINSHENGXUEGUANSHENGCHENGDENGFANGMIAN,ZUIZHONGDADAOYIZHIZHONGLIUSHENGZHANGDEMUBIAO。

       2018NIAN12YUE,BEIDASHENBAODEBPI-17509HEBPI-17509PIANDEYAOPINLINCHUANGSHIYANSHENQINGHUODEGUOJIAYAOPINJIANDUGUANLIJUSHOULI,BINGYUCINIANSHOUDAOGUOJIAYAOPINJIANDUGUANLIJUQIANFADEBPI-17509XIANGMUDE《LINCHUANGSHIYANTONGZHISHU》,PIZHUNKAIZHANZHILIAOGANNEIDANGUANAI、BANGGUANGAIHEFEILINAIDENGFGFRJIYINBIANYISHITILIUDELINCHUANGSHIYAN。

       夺宝岛YIZHIJIANCHIZIZHUCHUANGXIN,YONGYOUXIONGHOUDEYANFASHILI,ZIZHUYANFADECHUANGXINCHENGGUOYIJINGLUXUJINRUSHOUHUOQI,CHANPINGUANXIANHELINCHUANGYANJIUXIANGMURIYIFENGFU。BPI-17509XIANGMUSHI夺宝岛CHIXUSHENGENGZHONGLIUJINGZHUNYILIAOLINGYUQUDEDEYOUYIZHONGYAOCHENGGUO,JINYIBUTUOKUANLEGONGSIZAIZHONGLIUZHILIAOLINGYUDEBUJU,ZAITONGBADIANYAOWUZHONGJUYOUDUTEXINGZHI,GUONEIMUQIANSHANGWUTONGBADIANDEZHILIAOYAOWUSHANGSHI。


关于夺宝岛:

       夺宝岛GUFENYOUXIANGONGSI(GUPIAODAIMA:)SHIYIJIAYOUHAIGUIGAOCENGCIRENCAITUANDUICHUANGBANDE,YIZIZHUZHISHICHANQUANCHUANGXINYAOWUYANJIUHEKAIFAWEIHEXIN,JIYANFA、SHENGCHAN、YINGXIAOYUYITIDEGUOJIAJIGAOXINJISHUQIYE。ZIZHUYANFALEZHONGGUODIYIGEXIAOFENZIBAXIANGKANGAIYAO——YANSUANAIKETINI(SHANGPINMING:KAIMEINA),BEIYUWEIKANBIMINSHENGLINGYU“LIANGDANYIXING”DEZHONGDATUPO,LIANGHUOZHONGGUOZHUANLIJINJIANG,ZHANHUOWOGUOHUAXUEZHIYAOXINGYEDIYIGEGUOJIAKEJIJINBUYIDENGJIANG。JIEZHI2020NIANDIYIJIDUMO,AIKETINIYIHUIJI25WANMINGWANQIFEIAIHUANZHE,LEIJIXIAOSHOUJIN80YIYUAN。GONGSIJIANLILEWANZHENGDEXINYAOYANFATIXI,ZAIHANGZHOU、BEIJINGFENBIESHEYOUYANFAZHONGXIN,ZAIYANCHUANGXINYAO30YUXIANG,HANGAILEFEIAI、SHENAI、RUXIANAIDENGDUOGEZHONGLIUSHIYINGZHENG。GONGSIYUAmgen、Xcovery、Tyrogenex、Merus、Agenus、TIANGUANGSHI、YIFANGSHENGWUDENGGUONEIWAILINGXIANDEZHIYAOQIYEDACHENGZHANLVEHEZUO,WEICUJINQUANRENLEIDEJIANKANGFUZHIERGONGTONGNULI。


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